For example, a study implicating the endocannabinoid system as a regulator of the skin and its many biological processes touts CBD as a possible treatment for a variety of skin-related conditions (Bíró et al., 2009). Furthermore, CBD has been shown to have potent antioxidant and antimicrobial properties (Borges and da Silva, 2017; Martinenghi et al., 2020). In this article, we will explore one of the lesser-studied properties of CBD; its effects on energy. We will dive into how CBD can influence metabolism, mood, sleep, and other biological processes that regulate energy. CBD for energy, can it help? Let’s dive in.
CBD & Energy Levels
Although this area of cannabis research is relatively understudied, CBD has the capability to influence energy levels in a direct and indirect fashion. Due to the multitude of factors that influence energy levels, there is potential for CBD for energy products to indirectly alter how much energy we have. A study conducted in 2004 found that intracranial injection of CBD in rats increased wakefulness but decreased REM sleep (Murillo-Rodríguez et al., 2006).
Furthermore, a similar effect on sleep was observed when CBD was injected into the lateral hypothalamus, an area in the brain known to modulate sleep-wake cycles (Malfait et al., 2000). CBD has also been implicated in energy increase in human studies. It was found that 15 mg of CBD administered to young adults increased wakefulness during the sleeping time (Nicholson et al., 2004). In contradiction to these results, it was found that systemic administration of CBD (10 or 40 mg/kg) in rats increased the total percentage of sleep (Chagas et al., 2013).
Although these results are contradictory, it is evident that CBD has the potential to modulate wakefulness, and thereby influence energy levels. Neurochemically, it has been hypothesized that potential increases in wakefulness induced by CBD may be associated with Dopamine release. It is known that people who suffer from Parkinson’s disease are often deficient in Dopamine and experience daytime drowsiness. Furthermore, lesions of Dopamine neurons reduce arousal in animal models. Therefore, it is possible that CBD may increase alertness by activating neurons in the hypothalamus and increasing Dopamine release (Murillo-Rodriguez et al., 2014).